AIST to Advance Life Sciences Research With IBM Supercomputer

IBM's Blue Gene System to Be Engine for Protein Structure Prediction Research

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YORKTOWN HEIGHTS, NY & TOKYO - 07 Sep 2004: IBM announced today that AIST, a leading Japanese research laboratory, will use an IBM BlueGene/L supercomputer to advance their research in proteins, potentially accelerating breakthroughs in drug design.

The Computational Biology Research Center (CBRC) of The National Institute of Advanced Industrial Science and Technology (AIST) will use the extreme computational power of BlueGene/L to better predict 3-D protein structures, key to understanding how drugs interact with diseases. IBM Research and AIST are also exploring possible areas for joint research using application software IBM has specifically designed to tackle protein simulations on BlueGene/L.

Expected to be installed in February 2005, the BlueGene/L system will consist of four racks, with a peak processing speed of 22.8 trillion calculations per second, or 22.8 teraflops. The BlueGene/L supercomputer will be 24 times more powerful and use a fraction of the floor space compared to the CBRC's current computer systems. BlueGene/L consumes at most 1/10th the power per computation and 1/16th the floor space of systems of comparable compute power found on the Top 500 list of most powerful supercomputers.

"One of our biggest research challenges is to apply data obtained from genome decoding to protein engineering and drug design. The scale of simulation this requires cannot be done without the help of supercomputers," said Dr. Yutaka Akiyama, director, Computational Biology Research Center, AIST. "IBM's BlueGene/L supercomputer provides us with a massive supercomputing resource that will dramatically accelerate our work."

The AIST scientists are developing parallel and distributed computing techniques for solving large-scale data processing and searching problems in bioinformatics. The team is also creating high performance computer applications for molecular simulation, mass spectrometry analysis, and cell simulation.

"From the beginning, IBM's commitment to developing the most powerful and flexible supercomputers in the world has included a focus on tackling the biggest challenges in life sciences," said William Pulleyblank, director of exploratory server systems, IBM Research. "AIST's dedication to advanced life sciences research is the perfect opportunity to combine the world's most advanced supercomputer with a leading research institution to attack a major scientific challenge."

If it were installed today, this supercomputer would rank third in the world on the list of the Top 500 supercomputers announced in June 2004. Two early prototype BlueGene/L supercomputers were ranked as the fourth and eighth largest supercomputers in the world in June (http://www.top500.org/list/2004/06/). These systems exploit the advanced processors based on IBM's Power Architecture. Earlier this year, IBM announced its Power Everywhere initiative, designed to make this same IBM Power Architecture more widely available for everything from consumer electronics to supercomputers.